Support

Current

Industry

since 2006
Gilead Sciences & IOCB Research Center
supported by Gilead Sciences, Inc.

Public grant agencies

2019-2021
Cytostatic hetero-fused 7-deazapurine nucleosides, pharmacology, metabolism and mechanism of action (with P. Džubák/M. Hajdúch group)
Czech Science Foudation, 19-08124S

2018-2020
Bioconjugation reactions for cross-linking of proteins to DNA
Czech Science Foudation, 18-03305S

2018-2022
Chemical Biology for Development of Novel Therapies
European Regional Development Fund; OP RDE, CZ.02.1.01/0.0/0.0/16_019/0000729

2017-2019
Artificial epigenetics: Development of a eukaryotic bioorthogonal transcription system for gene expression manipulation in the cell (with L. Krásný group)
Czech Science Foudation, 17-03419S

2016-2021
Praemium Academiae to M. Hocek
Czech Academy of Academy of Sciences

2015-2019
Translational research and development of selective nucleotide kinase inhibitors for therapy of Alzheimer disease
Czech Health Research Council, 15-31984A

2015-2019
Click Chemistry for Future Gene Therapies to Benefit Citizens, Researchers and Industry (CLICKGENE)
International Training Network, European Commission (Horizon 2020)

Finished grants

2016-2018
Novel nucleosides and nucleotides derived from hetero-fused 7-deazapurines
Czech Science Foudation, 16-00178S

2012-2018
Center of novel approaches to bioanalysis and molecular diagnostics
Czech Science Foundation, P206/12/G151 (Center of excellence)

2014-2016
Modifications and bioorthogonal reactions in the major groove of DNA for regulation of protein binding and gene expression
Czech Science Foundation, 14-04289S

2012-2015
Development of novel methodologies of C-H activations of purines, deazapurines, pyrimidines and related heterocycles
Czech Science Foundation, P207/12/0205 (this grant is located at CU)

2011-2015
Combinatorial and rational approaches for the synthesis and evaluation of novel modified nucleosides with cytostatic anf antimicrobial activity
Czech Science Foundation, 207/11/0344

2009-2013
Construction of novel functional nucleic acids for applications in chemical biology, catalysis and self assembly
Czech Science Foundation, 203/09/0317

2009-2013
DNA labeling with redox markers for electrochemical sensing. Applications in analysis of nucleotide sequences and molecular diagnostics
Grant Agency of AS CR, IAA400040901

2009-2012
Development of modular syntheses of new C-nucleosides for studying DNA polymerase specificity and for the extension of the genetic alphabet
Grant Agency of AS CR, IAA400550902

2005-2011
Centre for New Antivirals and Antineoplastics
Ministry of Education of the Czech Republic, 1M0508

2005-2011
Center for Biomolecules and Complex Molecular Systems
Ministry of Education of the Czech Republic, LC512

2006-2011
Center of Chemical Genetics
Ministry of Education of the Czech Republic, LC06077

2005-2008
Interaction of DNA Polymerase alpha with Novel Base-Pairs
National Institute of Health, Fogarty International Center, R03 TW007372-01

2004-2007
Control of Assembly and Charge Transport Dynamics of Immobilized DNA
STREP project of 6th Framework EU, CIDNA

2005-2007
Conjugates of nucleobases with metal complexes as electroactive markers
Grant Agency of the Czech Republic, 203/05/0043